Download Free Medical Angio-protectors PowerPoint Presentation

Angio-protectors PowerPoint Presentation

DOWNLOAD MEDICAL POWERPOINT PRESENTATION

About This Presentation

Description : Check out this medical presentation on Pharmacology, which is titled "Angio (vaso)-protectors", to know about the angio (vaso)-protectors.

Tags : Pharmacology, Angio (vaso)-protectors

Published on : Jul 18, 2021 | Views : 2205 | Downloads : 0

Shareable Url :

Embed Code :

Comment

Transcript

Slide 1-

Angio (vaso)- protectors (Summary) Assoc. Prof. Iv. Lambev E-mail: itlambev@mail.bg Medical University of Sofia, Faculty of Medicine Department of Pharmacology and Toxicology
Slide 2-

I. Drugs improving capillary function (capillarotonic drugs) They reduce capillary fragility and permeability and prevent basal edothelium membrane damage. They act like antioxidants and prevent vitamin C and adrenaline oxidation. These drugs also inhibit lipid oxidation and synthesis of active oxygen species.
Slide 3-

Drugs improving capillary function  Bioflavonoids: Diosmin Hesperidin, Hyperoside, Naringin, Quercetin, Rutin Rutascorbin® (rutin/ascorbic acid)  Semisynthetic flavonoids: Troxerutin® Saponins: Escin (derived from Aesculus hippocastanum – Horse-chestnut) Combinations: Peflavit C®  Synthetic preparations: Calcium dobesilate (Doxium® – in retinopathy)
Slide 4-

Aesculus hippocastanum (Horse-chestnut)
Slide 5-

Bioflavonoids Fr. Cynosbati (Dog rose) Hb. Hyperici (St. John’s wort) Fr. Crataegi (Hawthorn) Fruits of citrus
Slide 6-

Hb. Hyperici (St. John’s wort)
Slide 7-

Fr. Crataegi (Hawthorn)
Slide 8-

are indicated in haemorrhagic diathesis, skin and retinal haemorrhages, different forms of capillary dysfunctions, radiation disease, infections and allergic diseases, varicose veins, atherosclerosis, hypertension, rheumatism, hepatitis, glomerulonephritis, meno- and methrorrhagias, paradontosis, drug capillary dysfunctions (caused by NSAIDs, glucocorticoids, reserpine, anticoagulants, arsenic compounds, gold salts). Drugs improving capillary function
Slide 9-

Atherosclerotic gangrene of foot
Slide 10-

Warfarin necrosis of breast skin 5 days after intaking of warfarin
Slide 11-

II. VENOTONIC DRUGS Detralex®, Endotelon®, Phelobodia® Troxerutin (Troxevasin®) Detralex® (diosmin/hesperidine) improves capillary functions, has venotonic and antiexudative action too, due to inhibition of PGs release. It inhibits leukocyte adhesion and migration. Detralex enhances lymphatic flow and drainage.
Slide 12-

Detralex®. Its venotonic effects is due to the prolonged NA action. Detralex improves skin perfusion and rheological properties of the blood. It is effective in chronic venous insufficiency, venous ulcer, hemorrhoids. Dosage: 2 x 1 tablet daily.
Slide 13-

Endotelon® is a purified and standardized extract of of grape seeds, contains procyanidolic oligomeres. It has endothelium protective and venotonic effects. Endotelon is prescribed p.o. in chronic venous and lymphatic insufficiency.
Slide 14-

Varicose veins Varicose ulcer
Slide 15-

Troxerutin (trihydroxyethylrutin) has venotonic, antiexudative and haemostatic activity. It improves capillary function and inhibits thrombocyte aggregation too. Troxerutin is used in varicose ulcers, chronic venous insufficiency, superficial thrombophlebitis, haemorrhoids, phlebo- sclerosis, muscle cramps, pain of traumatic origin (sprain, luxation). It is administered orally or locally, applied on the damaged area (2% gel).
Slide 16-

III. Heparin-containing… ointments (used in superficial thrombophlebitis and varicose veins): Heparoid®, Lioton® 1000 gel IV. Antihaemorrhoidal drugs Detralex® (orally) Doloproct® (fluocortolone/lidocaine): supp. and ointment Procto-Glyvenol® (tribenoside/lidocaie): supp. Ultraproct® (fluocortolone/cinchocaine): supp. and ointment