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Acute Respiratory Distress Syndrome (ARDS) PowerPoint Presentation

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Description : Respiratory failure (RF) is inability of the respiratory system to maintain a normal state of gas exchange from the atmosphere to the cells as required by the body

Tags : Acute Respiratory Distress Syndrome,ARDS,Respiratory failure

Published on : Aug 14, 2025 | Views : 566 | Downloads : 0

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ARDS
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PATHOPHYSIOLOGY OF RESPIRATORY FAILURE Respiratory failure (RF) is inability of the respiratory system to maintain a normal state of gas exchange from the atmosphere to the cells as required by the body The role of the respiratory system is to maintain normal arterial blood PO2, PCO2, and pH
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Definition: RF is present if: (1) Arterial PO2 (PaO2) is < 60 mm Hg, or (2) Arterial PCO2 (PaCO2) is > 45 mm Hg, except when the elevation in PCO2 is compensation for metabolic acidosis A PaO2 < 60 mm Hg, indicating hypoxemic respiratory failure, is valid during room air breathing [FIO2] = 0.21, but hypoxemia while breathing supplemental oxygen also indicates respiratory failure
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Classification: Disorders that affect the lungs including: - airways, - alveolar spaces - interstitium - pulmonary circulation Disorders that affect primarily the non-lung components of the respiratory system
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Hypoxic respiratory failure
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History : Ashbaugh 1967 Definition : 1994
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Why low PaO2 ? O2 dissolution CO2 dissolution
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Precipitating factors
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Pathology of ALI Exudative phase Proliferative phase Fibrosing phase
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Treatment of the cause
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