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The Beginning of Human Life and Prevention of Chronic Disease: Reframing the First 1,000 Days PowerPoint Presentation

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Description : This medical presentation on "The Beginning of Human Life and Prevention of Chronic Disease: Reframing the First 1,000 Days" was delivered during Global Wellness Summit. The presentation talks about The first 1000 days of human development including preconcetpion and pregnancy phases etc.

Tags : wellness, medical, healthcare, wellness, preconcetpion phase, pregnancy phase

Published on : Jul 19, 2020 | Views : 3333 | Downloads : 3

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The Beginning of Human Life and Prevention of Chronic Disease: Reframing the First 1,000 Days Paradigm Sergio Pecorelli MD,PhD University of Brescia, Italy The Breakers Palm Beach 9-11 October 2017
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PREVENTION BEGINS BEFORE CONCEPTION
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Application of knowledge and advanced technologies, to develop an innovative care process that integrates clinical molecular and exposome evaluation, education and empowerment, monitoring via wearables devices. A multi-disciplinary approach providing translational tools for early diagnosis/treatment of obstetrical, developmental and chronic disorders affecting children and future generations. A novel ground-breaking effort that will collect pregnancy-related samples and data from parents and children from before conception to about two years of life.
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low risk trajectory Risk Mother and infant eﬀective point to intervene Child/adolescent eﬀective point to intervene Adult: screening may be too late to reduce risk Aﬀected adult: interventions have limited eﬀect Plasticity Detrimental effects of lifestyle challenges/increasing mismatch The first1000days of human development including preconcetpion and pregnancy phases accounts for the 70% of individual future life. Life course 1000 days in a lifetime Future Parents Prepare For Conception Preconception
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60+ 3b % rldwide tion Number 2030 2.0 Number 60+ 21 2014 1.3b of total wo popula 868m 16% Number 60+ of total worldwide 12% population of total worldwide 2050 Aging population and chronic diseases rise 0 2 4 6 8 10 12 2000 population 2005 2010 2015 2020 2025 2030 Deaths in millions Cancer Ischaemic heart disease Cerebrovascular disease Acute respiratory infections Perinatal conditions HIV/AIDS Road traffic accidents Tubercolosis Malaria
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Modern lifestyle Diets Microbial patterns Physical excercise Inflammation and altered immune functions Multisystem effect Tissue damage, oxidative stress and tissue repair Mood, behaviour, development, degeneration Cardiovascular response Gastrointestinal inflammation Lung development and fuction Joints and tissues Stress and HPA responses Metabolic responses Increased NCD risk The most effective anti-inflammatory medicine Health stressors Hormonal factors Behavioral factors Chemical stressors Non-chemical stressors
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Pre- mature death High-level wellness Wellness paradigm Neutral point (no discernable illness or wellness) Disability Symptoms Signs Treatment paradigm Awareness Education Growth Illness-wellness continuum “Wellness educates for healthy lifestyles and promotes prevention” 52% of world population 5% of world population
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Fetal life Adolescence Adult life Infancy and childhood Cumulative incidence Genetic susceptibility Pre-conception Chronic disease prevention: a life course approach Older ages
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Putative effects of exercise and obesity on the predisposition to metabolic diseases
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Wellness lifestyles (especially exercise training) have the potential to modify the epigenome of human reproductive cells and could have an unprecedented affect on the health of future generations influencing offspring health and disease risk. I Generation II Generation III Generation The epigenetic inheritance
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Dimension of health and wellness Spiritual Emotional- mental Social Health and wellness are a multi-dimensional entangled universe Intellectual Physical
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Sound scientific evidence proves that wellness plays a key role in population’s health in synergy with the traditional medical paradigm Children’s wellness (pre-conception and the first1000 days) represents a critical period to prevent Non Communicable Diseases and to enhance the individual mindfulness for the rest of the lifespan Health and wellness professionals should promote and apply the educational role of wellness for primary and secondary prevention in shaping the new prevention paradigm and ensure the sustainability of the Healthcare systems. Take Home messages
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Sergio Pecorelli MD,PhD sergio.pecorelli@unibs.it s.pecorelli@pecosmethod.com www.pecosmethod.com Thank you!
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