Radiation therapy Medical Presentation

Radiation Therapy PowerPoint Presentation

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Tags : radiation therapy, bravhytherapy,cancer

Published on : Oct 09, 2018 | Views : 2344 | Downloads : 0

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Slide 1-

Aim 1. To evaluate the 3-d dose distribution among Ir-192 source and Xoft applicator using PRESAGE dosimeters. 2. Assess dose from Xoft’s Henscke type cervical applicators and the standard Ir-192-based fletcher suit applicators using TLD dosimeters. 3. Focus on dose to cervix and ovules Supervisor : Dr. Ramachandran Prabhakaran Partner institution : Peter MacCallum cancer centre
Slide 2-

Electronic Brachytherapy eBx - Brachytherapy with Miniature Electronic X-ray Sources conceived in the 1980s by Alan Sliski of PhotoElectron Corp. in collaboration with MIT Cobalt 60 vs Linac
Slide 3-

Radionuclide vs Electronic eBx More than 500 HDR accidents (including one death) have been reported along the entire chain of procedures from source packing to delivery of dose.
Slide 4-

eBrachy vs other therapy systems DJ EATON, BJR 2015
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Electronic Brachytherapy Machines Xoft (iCAD) Intrabeam (Zeiss) Esteya (Elekta) Photoelectric therapy (Xstrahl) SRT 100 (Sensus Healthcare) Papillon (Ariane)
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eBrachy machines Axxent X-ray Source mimics certain characteristics of the most common HDR brachytherapy isotope 192Ir Unique combination of high dose rate and low energy radiation DJ EATON, BJR 2015 DJ EATON, BJR 2015
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iCAD Inc Xoft anode: Tungsten film on an aluminum nitride substrate with yttria binder –Tungsten L-lines at 8.4, 9.8 and 11.3 keV –Yttrium K-lines at 14.9 and 16.7 keV
Slide 8-

Xoft x-ray tube vs conventional tube
Slide 9-

Xoft Cervical Applicator Set Henschke type applicator Thin wall titanium design CT compatible Multiple tandem angles – 0° – 15° – 30° – 45° Multiple ovoid diameters – 2.0 cm – 2.5 cm – 3.0 cm 50 cm source catheter length gauge
Slide 10-

Coronal view of the Xoft Henschke applicator
Slide 11-

Dosimetric comparison (Ir-192 vs Xoft) Xoft
Slide 12-

DVH comparison
Slide 13-

Methodology 1. Design phantoms to accommodate Fletcher suite and Electronic brachytherapy cervical applicators 2. Measurement of dose along the radial and applicator long axis using EBT3 films and TLDs for Ir-192 and eBx brachytherapy applicators. 3. Comparison of measured and estimated dose along the radial axis for both Ir-192 and eBx 4. Reconstruction of 3D dose distribution using Presage dosimeter 5. Measurement of surface dose at the applicators
Slide 14-

References 1. Valentin J. Preface, Main Points, Introduction, Chapters and 3. Annals of the ICRP. 2005;35(2):1-9 2. Kirk M, Coon A, Dickler A, Bernard D, Zusag T. A dosimetric comparison of Xoft Axxent Electronic BrachytherapyTM and Ir-192 HDR interstitial brachytherapy in the treatment of cervical cancer. Brachytherapy. 2008;7(2):153. 3. Eaton D. Electronic brachytherapy—current status and future directions. The British Journal of Radiology. 2015;88(1049):20150002. 4. Ramachandran P. New era of electronic brachytherapy. World Journal of Radiology. 2017;9(4):148