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Pagets Disease of Bone PowerPoint Presentation

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Description : Check out this medical PowerPoint presentation titled "Paget’s Disease of Bone” by Ethel S. Siris and G. David Roodman.

This medical PowerPoint presentation is about Pagets disease of bone, also known as osteitis deformans. Pagets disease of bone is a chronic bone disorder characterized by the abnormal breakdown and formation of bone tissue, leading to weakened and deformed bones.

The disease typically affects the elderly population, and the exact cause is unknown, although genetic and environmental factors are believed to play a role.

Symptoms may include bone pain, joint stiffness, deformities, and fractures. In some cases, the disease may be asymptomatic and only detected through routine X-rays or blood tests.

There is no cure for Pagets disease of bone, but treatment can help alleviate symptoms and slow the progression of the disease. Medications such as bisphosphonates and calcitonin can help regulate bone turnover, and surgery may be necessary in cases of severe bone deformity or fracture. Regular monitoring and management of the disease are essential to prevent complications.

Tags : Paget’s Disease of Bone, osteitis deformans, bone tissue, Orthopaedic Surgery, Orthopaedic Surgery PowerPoint presentation

Published on : Jun 23, 2023 | Views : 1392 | Downloads : 0

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Slide 1-

Chapter 72: Paget’s Disease of Bone Ethel S. Siris and G. David Roodman
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Figure 1 Figure 1 Scanning electron micrographs with sections of normal bone (left) and pagetic bone (right). Both samples were taken from the iliac crest. The normal bone shows the trabecular plates and marrow spaces to be well preserved, whereas the pagetic bone has completely lost this architectural appearance. Extensive pitting of the pagetic bone is apparent caused by dramatically increased osteoclastic bone resorption. [Photographs courtesy of Dr. David Dempster; reproduced with permission from Lippincott from Siris ES, Canfield RE 1995 Paget’s disease of bone. In: Becker KL (ed.) Principles and Practice of Endocrinology and Metabolism, 2nd ed. JB Lippincott, Philadelphia, PA, USA, pp. 585–594 (http://lww.com).] From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition. www.asbmrprimer.org
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Figure 2 Figure 2 Radiograph of a humerus showing typical pagetic change in the distal half, with cortical thickening, expansion, and mixed areas of lucency and sclerosis, contrasted with normal bone in the proximal half. © 2008 American Society for Bone and Mineral Research From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition. www.asbmrprimer.org
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Figure 3 Figure 3 Typical “cotton-wool” appearance of an enlarged pagetic skull with marked osteoblastic change. The patient had an increase in head size and deafness. © 2008 American Society for Bone and Mineral Research From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition. www.asbmrprimer.org