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Breast Cancer Treatment: A Multidisciplinary Team Approach PowerPoint Presentation

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Description : Check out this medical presentation on Breast Cancer (Inflammatory), which is titled "Breast Cancer Treatment: A Multidisciplinary Team Approach", to know about breast cancer treatment approaches.

Tags : Breast Cancer, Inflammatory, Treatment, Radiology, Pathology, Surgery, Radiation Oncology, Medical Oncology

Published on : May 10, 2021 | Views : 1971 | Downloads : 5

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Slide 1-

Breast Cancer Treatment: A Multidisciplinary Team Approach Radiology Pathology Surgery Radiation Oncology Medical Oncology Fighting the Crab – Kiev, Ukraine
Slide 2-

Julie R. Gralow, M.D. Director, Breast Medical Oncology, Seattle Cancer Care Alliance Professor, Medical Oncology, University of Washington School of Medicine Member, Clinical Division, Fred Hutchinson Cancer Research Center Treatment Overview: The Multidisciplinary Team
Slide 3-

Personalized Cancer Medicine New Strategies in Treating Breast Cancer: Better Targeting Individualized Approaches
Slide 4-

Cancer Treatment: Defining the Cancer The first step in designing the treatment plan is carefully defining the cancer Clinical examination Radiology tests Pathology tests Blood tests
Slide 5-

Diagnosing the Cancer: Ultrasound-Guided Breast Biopsy
Slide 6-

Defining the Cancer: Pathology Treatment recommendations are aided with the help of pathologic factors Prognostic factors: aid in estimating likelihood of cancer recurrence and death Predictive factors: predict likelihood of response to a given therapy
Slide 7-

The First Step in Making a Treatment Plan for Breast Cancer: Defining the Cancer Stage Tumor size Lymph node status Metastatic sites Grade Surgical margins Tumor expression of genes and proteins Estrogen receptor (ER) Progesterone receptor (PR) HER-2 Estrogen Receptor Invasive Breast Cancer HER-2
Slide 8-

Defining the Cancer: Radiology Radiologic imaging can help determine the location and spread of the cancer Local extent Regional lymph nodes Distant spread (metastases)
Slide 9-

Mammogram: Area of abnormality extends over 60 mm Evaluating Extent of Local Disease: Breast Cancer
Slide 10-

Bone Scan Staging for Distant Disease: Breast Cancer Multiple bone metastases Patient A The most common sites of distant disease in breast cancer are the bones, liver and lungs
Slide 11-

Breast Cancer Surgery Sometimes “less” surgery is better Mastectomy vs. lumpectomy Lymph node dissection vs. sentinel lymph node biopsy
Slide 12-

Lumpectomy: Wire Localization of Non-Palpable, Imaging-Detected Breast Cancers
Slide 13-

Lumpectomy Margin Evaluation: Inking the Tumor Specimen in the Operating Room
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Sentinel Lymph Node Biopsy 1. Inject around area of tumor with blue dye, radioactivity, or both 2. Track the lymphatic drainage of the tumor sentinel node biopsy requires substantial technology, resources, and training
Slide 15-

Breast Cancer Radiation Therapy The future: is “less” radiation sometimes better? Whole breast versus partial breast radiation (brachytherapy) Hypofractionation (shorter course) 3D conformal radiation planning
Slide 16-

Indications for Radiation Therapy After Mastectomy Tumor size > 5 cm Inflammatory features or skin involvement Multiple positive lymph nodes Extracapsular lymph node extension Positive surgical margins
Slide 17-

Systemic Therapy for Breast Cancer Endocrine Therapy Chemotherapy Biologically-targeted Therapy New Strategies: Individualizing treatment to the cancer and the patient
Slide 18-

Identifying New Targets in the Treatment of Breast Cancer Death Receptors Tubulin-interacting Agents HDAC Inhibitors Metastasis Inhibitors Anti-Angiogenesis HER-2 Inhibitors IGF-R Inhibitors MUC-1 Antibodies Proteosome Inhibitors mTOR Inhibitors Farnesyl Transferase Inhibitors Mdm2 Inhibitors Pro-apoptotic Drugs Kinesins Aurora Kinase Inhibitors MEK Inhibitors HIF Inhibitors Raf Inhibitors EGFR Inhibitors HSP90 Inhibitors Src Inhibitors Cell Cycle Inhibitors
Slide 19-

Optimizing Health and Wellness After Treatment of Breast Cancer: Survivorship Many breast cancer patients can look forward to a long life after treatment Breast cancer patients and their health care team need to pay attention to all aspects of health and well-being Team Survivor Northwest