Download Free Medical Protein Synthesis PowerPoint Presentation

Protein Synthesis PowerPoint Presentation

DOWNLOAD MEDICAL POWERPOINT PRESENTATION

About This Presentation

Description : Check out this medical presentation on Genetics, which is titled "Protein synthesis", to learn about Protein synthesis, the making of proteins by the cell with the help of RNA.

Tags : Genetics, Protein synthesis, RNA

Published on : Aug 29, 2021 | Views : 4145 | Downloads : 9

Shareable Url :

Embed Code :

Comment

Transcript

Slide 1-

Protein synthesis: the making of proteins by the cell With the help of RNA
Slide 2-

So far we’ve discussed one type of nucleic acid: DNA A second type of nucleic acid is RNA. Like DNA, RNA is made up of three nucleotides. A five carbon sugar, a phosphate and a nitrogenous base.
Slide 3-

The five carbon sugar of RNA is called ribose. The phosphate group is the same as DNA RNA also has four bases except it lacks thymine. It has a base called uracil instead of thymine. Uracil pairs with adenine. U-A
Slide 4-

In all, there are three differences between RNA and DNA
Slide 5-

ppt slide no 5 content not found
Slide 6-

ppt slide no 6 content not found
Slide 7-

There are three types of RNA molecules. Each has a different function in making or synthesizing proteins. 1. Messenger RNA (mRNA) – carries DNAs message from the nucleus to the ribosome.
Slide 8-

2.Transfer RNA (tRNA)– carries the correct amino acids to the ribosome so they can be added to the growing protein chain.
Slide 9-

3. Ribosomal RNA (rRNA)– makes up part of the ribosome. Helps read mRNAs message and assemble proteins.
Slide 10-

ppt slide no 10 content not found
Slide 11-

There are two steps in protein synthesis. Transcription Translation
Slide 12-

Two steps to protein synthesis 1. Transcription – mRNA is made from the DNA code. It occurs in the nucleus where the DNA is located. Involves DNA and mRNA
Slide 13-

2. Translation: Protein is made by adding amino acids to a growing peptide chain. It occurs at the ribosome where proteins are made. Involves mRNA, rRNA and tRNA.
Slide 14-

Making Proteins DNA: TAC CGA TCG TGA ACT mRNA: AUG GCU AGC ACU UGA Protein: Met-Ala-Ser-Thr-Stop
Slide 15-

Protein synthesis in detail. Transcription: mRNA is made from the DNA code in the nucleus The entire DNA code is not copied. Just one gene segment that codes for a specific protein
Slide 16-

Transcription explained in steps: 1. The enzyme RNA polymerase, unwinds DNA and guides the creation of mRNA. 2. The DNA double helix unwinds and separates at a certain point. RNA polymerase uses one strand as a template or model Transcription animation http://www.fed.cuhk.edu.hk/~johnson/teaching/genetics/animations/transcription.htm
Slide 17-

3. Nucleotides are added into a complimentary strand of mRNA based on the DNA code. DNA: AATTGGCAC mRNA: UUAACCGUG 4. This mRNA strand leaves then nucleus and goes to the ribosome for translation
Slide 18-

RNA DNA RNA polymerase TRANSCRIPTION: label the diagram Section 12-3 Adenine (DNA and RNA) Cystosine (DNA and RNA) Guanine(DNA and RNA) Thymine (DNA only) Uracil (RNA only) Go to Section:
Slide 19-

2. Translation mRNA is now at the ribosome where amino acids are added to make a long protein chain. Its still based on the DNA code which is carried by mRNA.
Slide 20-

Translation explained in steps The mRNA is read by rRNA. rRNA makes up the ribosome. 2. mRNA is read three bases at a time. Every three bases on mRNA codes for one amino acid and is called a codon. Codon: Three bases on mRNA that codes for one amino acid.
Slide 21-

3. Tranfer RNA or tRNA carries the correct amino acid to the ribosome. It also reads the mRNA codon with rRNA Anticodon: three bases on tRNA that are complimentary to mRNA mRNA codon: UUC tRNA anticodon: AAG
Slide 22-

4. Amino acids are brought until the entire mRNA is read. Each tRNA drops off one amino acid then goes into the cytoplasm to grab another. 5. The ribosome bonds each amino acid together using a peptide bond creating a polypeptide. Eventually the stop codon is reached and the final amino acid is added.
Slide 23-

ppt slide no 23 content not found
Slide 24-

Single amino acid Growing polypeptide chain bonded with peptide bonds Transfer RNA carrying amino acids Part of mRNA The ribosome is made of rRNA and proteins.
Slide 25-

6. Finally, the protein is shipped to the golgi body where it is altered and shipped to where it needs to go. 7. At its final destination, the protein will perform the job it was created to do.
Slide 26-

HOW DOES RNA POLYMERASE KNOW WHERE TO START mRNA has a start codon, a specific three letter nucleotide sequence that says begin here. The start codon on mRNA is the three letters AUG Remember how big DNA is. The entire molecule is not used to make mRNA. Just a small portion. A stop codon tells RNA polymerase to stop making the protein.
Slide 27-

Transcription and translation animation http://learn.genetics.utah.edu/content/begin/dna/transcribe/ Transcription and translation animation http://www.pbs.org/wgbh/aso/tryit/dna/shockwave-nojs.html
Slide 28-

Your body is made mostly of proteins. Your skin pigments are proteins. Part of you blood and vessels are made of proteins. Your muscles, brain, enzymes, etc are all made partly of proteins. Your ribosomes are continuously making them. You have thousands in each cell of your body.
Slide 29-

Several factors determine the differences between all the proteins in your body. 1. the order of amino acids: you change the order and you change the protein and its function. 2. shape of the protein: the golgi shapes the protein after its assembled. You change the shape, you change the protein and function. Denature: The shape of a protein is changed and it stops working.
Slide 30-

ppt slide no 30 content not found
Slide 31-

Several things can cause a protein to denature heat: each protein function at a specific temperature. Heat changes the shape, therefore changes function. High fevers can be dangerous to your body. 2. pH: each protein functions at a specific pH. Increase or decrease can damage it. 3. chemical: exposure to chemicals such as heavy metals
Slide 32-

One skill you need for the regents exam is to create a protein when given a DNA code. You will need to use this amino acid chart Remember the bases for DNA are GCAT RNA are GCAU
Slide 33-

1. When given a DNA code, you must first transcribe it into mRNA Do this by complimentary base pairing. A-U G-C DNA: TACTTGAACTAA mRNA: AUGAACUUGAUU
Slide 34-

2. Next break the mRNA into codon or three letters. DNA: TACTTGAACTAA mRNA: AUGAACUUGAUU mRNA: AUG-AAC-UUG-AUU This particular mRNA was broken into four codons. How many amino acids will this protein be?
Slide 35-

3. Plug the codons into the chart and find the amino acids. mRNA: AUG-AAC-UUG-AUU Amino acid: met-asp-leu-iso Interactive: http://www.learner.org/interactives/dna/engineering4.html
Slide 36-

64 POSSIBLE CODONS
Slide 37-

. Label the diagram below Go to Section:
Slide 38-

Summary of protein synthesis: Protein synthesis takes place in 2 steps: Transcription and translation 1. Transcription: DNA unzips mRNA is made by complimentary base pairing Happens in the nucleus.
Slide 39-

2. Translation: mRNA leaves the nucleus and goes to the ribosome. At the ribosome, a specific protein is made. This is done by tRNA adding amino acids to a growing chain. http://www.edumedia-sciences.com/en/a71-protein-synthesis http://library.thinkquest.org/20465/g_DNATranscription.html
Slide 40-

Making Proteins DNA: TAC CGA TCG TGA ACT mRNA: AUG GCU AGC ACU UGA Protein: Met-Ala-Ser-Thr-Stop
Slide 41-

GCC: AUG: UUU:: ACG: CGU: TTT:
Slide 42-

CCC: GCA UUU AUG AGG AAA CGC ATG:
Slide 43-

Starting with DNA, find the mRNA code, and the amino acid sequence using one of the charts. DNA: ATATTTGCCGAA mRNA: UAU-AAA-CGG-CUU tRNA: AUA-UUU-GCC-GAA Amino acid: Tyr-Phe-Ala-Glu Use mRNA in the amino acid chart
Slide 44-

Do these on your own: DNA: GCCATTTAACGG mRNA: Amino acid: DNA: AATTCCGGATAT mRNA: Amino acid:
Slide 45-

DNA: GGCCCTATTGGG mRNA: _________________ Amino acid: __________________ DNA: TACCCCCGATTACGTACC mRNA: __________________________ Amino acid: ___________________________