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Submandibular gland: Surgical Anatomy Tumors Surgery PowerPoint Presentation

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Description : Check out this medical presentation on cancer titled "Submandibular gland: Surgical Anatomy Tumors Surgery" to know about Submandibular gland, its surgical anatomy and tumor surgery.

Tags : Cancer, Submandibular gland, Surgical Anatomy, Tumors Surgery, Submandibular ganglion, Submandibular duct, Lingual nerve, Salivary Gland Tumors, risk factors

Published on : May 05, 2021 | Views : 2466 | Downloads : 5

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Slide 1-

Submandibular gland: Surgical Anatomy Tumors Surgery Dr Amit Gupta Associate Professor Dept Of Surgery
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Surgical Anatomy Composed of a superficial part and a deep part. Superficial part: lies in the submandibular triangle between two bellies of digastric muscle Deep part: lies below and lateral to the line of the submandibular duct, in the floor of the mouth, above and deep to the mylohyoid.
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Borders Lateral – proximal half of the mandible. Posterior – anterior to but near the low anterior margin of the parotid gland. Inferior – approaches the level of the hyoid bone. Majority of gland lies over the external surface of the mylohyoid muscle. Lateral to and abuts the lingual and hypoglossal nerve and is medial to the marginal mandibular and cervical branch of the facial nerve. Drains through Wharton’s duct in anterior floor of the mouth Lymphatic Drainage Level IB
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Submandibular ganglion is attached to the nerve at this point and is also within the sheath of the gland Submandibular duct lies beneath the lingual nerve as it emerges from the upper pole of the gland. Lingual nerve lies first between the duct and the deep part of the gland, then crosses medially beneath the duct to ascend on the hyoglossus to supply the tongue. In some subjects a posterior sublingual gland drains into the submandibular duct Bartholin's major sublingual gland may drain via A single duct into the submandibular duct or by a separate open
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Salivary Gland Tumors
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Relatively uncommon – 2% of head and neck neoplasms Diverse histopathology Distribution Parotid: 80% overall; 80% benign; 25% malignant Submandibular: 15% overall; 50% benign;43%malignant Sublingual/Minor: 5% overall; 40% benign;65%malignant Epidemiology
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Preponderance of benign tumors in women Malignant tumors exhibit an equal sex distribution Patients with benign tumors are younger (mean age: 46 years) compared with those with malignant tumors (mean age: 54 years) Trend to an older age for submandibular and minor salivary gland locations
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Risk factors Nutrition: low intake of vitamins Smoking Irradiation Ultraviolet exposure (controversial)
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Molecular targeting Recent interest in molecular targeting of salivary gland malignancies Molecular markers EGFR Overexpression in all histologic subtypes HER2 Ductal carcinoma C-kit Adenoid cystic Although there is overexpression of these molecular markers, the rates of true genetic mutation is much lower
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Clinical Presentation Painless, rapidly enlarging mass Indolent period >10 years Pain is more frequently associated with malignant disease Clinical features suggesting a malignant tumour: Rapid growth rate Pain Facial nerve palsy Childhood occurrence Skin involvement Cervical adenopathy
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WHO classification of salivary gland tumors
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Morphology Pleomorphic adenomas: originate from the intercalated duct cells and myoepithelial cells Oncocytic tumors: originate from the striated duct cells Acinic cell tumors: originate from the acinar cells Mucoepidermoid & squamous cell carcinomas: develop in the excretory duct cells.
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Diagnostic Work-Up History /Physical Examination Computed tomography (CT) scans Magnetic resonance imaging (MRI) (T1-weighted images are excellent to assess the margins, deep extent, and patterns of infiltration because the (fatty) background of the gland is hyperintensive) Perineural invasion may be evaluated with both CT and MRI PET CT Scan Potential role for staging and management in salivary gland carcinomas Fine-needle aspiration cytology
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Axial CT scan showing left submandibular gland lesion
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MRI scan showing right submandibular gland lesion
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PET CT scan showing right submandibular gland lesion
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Treatment Surgery Radiotherapy Chemotherapy (not efficacious)
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Surgery Mainstay of treatment Submandibular Gland excision with level Ib dissection recommended Radical resection is indicated with tumors that invade the mandible, tongue, or floor of mouth
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Submandibular Triangle Dissection Scalpel proceeds through the skin in a curvilinear incision from just off the midline anteriorly to just below the earlobe posteriorly Flap is elevated deep to platysma muscle Surgeon must be aware of the course of the marginal branch of the facial nerve. It is important to identify this nerve and mobilize it anteriorly and posteriorly.
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Incision for combined neck dissection Incision site for submandibular triangle dissection Skin flap raised superiorly with platysma muscle left in place
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Skin flap raised superiorly with platysma muscle Marginal branch of the facial nerve and its relationship with the facial vessels
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Detail of the submandibular triangle with the submaxillary gland resected
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Management of Neck
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Management of the N0 neck Tumors >4cm High grade histology Management of the N+ neck Ipsilateral MRND for clinically or radiographically positive nodes Incidence of multilevel node involvement
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Postoperative Radiotherapy Indications T3-4 tumors Close or positive margin Incomplete resection Bone involvement Perineural invasion Positive nodes Recurrent cancer
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Prognosis Survival of patients with submandibular cancers is inferior to that of parotid cancers Perineural invasion: independent prognostic factor for distant metastases or DFS Impairment of function of the facial nerve : poor DFS Acinic cell and (low-grade)mucoepidermoid cancer: best prognosis Undifferentiated & squamous cell cancer: worst prognosis