Download Free Medical Ribosomal RNA PowerPoint Presentation

Ribosomal RNA PowerPoint Presentation

DOWNLOAD MEDICAL POWERPOINT PRESENTATION

About This Presentation

Description : Check out this medical presentation on Genetics, which is titled "Ribosomal RNA", to learn about Ribosomal RNA (rRNA).

Tags : Genetics, Ribosomal RNA, rRNA

Published on : Aug 29, 2021 | Views : 2338 | Downloads : 0

Shareable Url :

Embed Code :

Comment

Transcript

Slide 1-

Ribosomal RNA Phillips Huang BMS 265
Slide 2-

rRNA Nomenclature Named based on sedimentation rates, measured in Svedberg units (S) Larger sedimentation coefficients indicate faster sedimentation rates Larger rRNAs sediment faster
Slide 3-

rRNA Discovery First discovered in the 1930s as part of the microsome by Albert Claude Characterized as a ribosomal component in the 1950s by George Palade
Slide 4-

Large Ribosomal Subunit rRNA largely responsible for 3D structure Peptidyl transferase center (PTC) composed of rRNA A, P and E sites made up mainly of rRNA
Slide 5-

Small Ribosomal Subunit Atomic structure published in 2000 Decoding center composed entirely of rRNA
Slide 6-

rRNA Biogenesis in Eukaryotes In prokaryotes, rRNAs are also synthesized as one primary transcript
Slide 7-

Mechanism of action: Translation initiation in Prokaryotes Translation initiation in eukaryotes involves binding of ribosomal components first to the mRNA 5’ cap
Slide 8-

Mechanism of action: Translation elongation Residues of rRNA help to stabilize the mRNA:tRNA complex
Slide 9-

Peptide Bond Formation Involves nucleophilic attack of α-amino group of aminoacyl-tRNA on carbonyl carbon of peptidyl-tRNA Hypothesized transition state Target carbonyl carbon is protected from hydrolysis prior to reaction
Slide 10-

Mechanism of action: Translation termination
Slide 11-

rRNA as a Tool Phylogenetic studies rRNA sequences are highly conserved across species In vitro translation systems Used when overexpressed protein is toxic, rapidly degraded or insoluble in cells lancelets hagfish lamprey gnathostome
Slide 12-

Role in Human Disease Mutations in mitochondrial rRNA Susceptibility to aminoglycoside-induced hearing loss Changes to rRNA in cytoplasmic ribosomes Defective pseudouridylation and X-linked Dyskeratosis Congenita (X-DC)
Slide 13-

ppt slide no 13 content not found

User Presentation
Related Presentations

CHROMOSOME ORGANIZATION AND MOLECULAR STRUCTURE

CHROMOSOME ORGANIZATION AND MOLECULAR STRUCTURE

By: JenniferDwayne
Views: 3177

Mechanisms and Management of Labor

Mechanisms and Management of Labor

By: JenniferDwayne
Views: 2793

Neural Communication-Basics

Neural Communication-Basics

By: JenniferDwayne
Views: 2307

Medical Imaging

Medical Imaging

By: JenniferDwayne
Views: 3422

Urinary System

By: JenniferDwayne
Views: 2048

Genes Genomics and Chromosomes

Genes Genomics and Chromosomes

By: JenniferDwayne
Views: 2672

Mendel and Heredity

Mendel and Heredity

By: drdwayn
Views: 2061

GENSKE BOLESTI

By: martinatr99
Views: 1966

Challenges in and Principles for Conducting Systematic Reviews

Challenges in and Principles for Conducting Systematic Reviews

By: KhushbuSG
Views: 1064

Sickle Cell Disease-Epidemiology Genetics Pathophysiology

Sickle Cell Disease-Epidemiology Genetics Pathophysiology

By: FrankMarco
Views: 1591

About : Professor, College of Nursing and Health Sciences
Occupation : Medical Professional
Specialty : MD
Country : United States of America
Website :

HEALTH A TO Z

Feedback