Download Free Medical Constipation PowerPoint Presentation

Constipation PowerPoint Presentation

DOWNLOAD MEDICAL POWERPOINT PRESENTATION

About This Presentation

Description : Check out this medical presentation on Constipation and Defecation Problems, which is titled "Constipation", to know about the physiology of defecation and understand the differences between constipation, encorporesis, and soiling. Also, identify major causes of constipation, know the differences between functional and organic causes, and understand the principle behind constipation management.

Tags : Constipation, Defecation Problems, encorporesis, soiling

Published on : Jul 10, 2021 | Views : 4222 | Downloads : 9

Shareable Url :

Embed Code :

Comment

Transcript

Slide 1-

CONSTIPATION Dr. Soad Jaber 2009
Slide 2-

Constipation Physiology of defecation Understand the differences between Constipation Encorporesis Soiling Identify major causes of constipation Differences between functional and organic causes Understand the principle behind constipation management
Slide 3-

CONSTIPATION Physiology of defecation In normal subjects : Distention of the rectum Reflex relaxation of internal sphincter Contraction of external sphincter *Lower rectum is normally empty *Entry of fecal material from above gives the sensation of the need to defecate. If the rectum is chronically distended the sensation is lost  retention of stool  full rectum
Slide 4-

Constipation: Delay or difficulty in defecation that has been present for two weeks or longer. is associated with anal and abdominal discomfort. Full rectum
Slide 5-

Functional Constipation: Is a voluntary withholding of stools Starts after the neonatal period Usually develop after passage of painful bowel movement.
Slide 6-

Encopresis: Day or night time passage of formed stool into inappropriate places beyond the age expected for toilet training (4-5 year Abnormal anal sphincter physiology.
Slide 7-

Types of Encopresis: A)RETENTIVE encopresis with constipation and overflow incontinence.2/3 B)Non RETINTIVE encopresis: without constipation and overflow.1/3 OR :1ry from infancy occur with global developmental delay and enuresis. 2ry:after successful toilet training occur with psychosocial stress and mismanagement
Slide 8-

Soiling: Involuntary escape of fluid or semi fluid stools into the under clothing usually due to overflow from a loaded cecum with feces which leads to stretch of internal sphincter
Slide 9-

Neurogenic Soiling: Soiling which occur due to neurological abnormalities: Spinal bifida Paraplegia Myelomengiocel
Slide 10-

Causes of Constipation: Infants and Children: 1. Non-organic Causes .Lack of dietary fibers .Inadequate fluid intake .Failure to develop regular bowel habits (neglect, stubborn child, MR) .Follow illness .Change in environment or routine (Holidays… school entry)
Slide 11-

Organic cause Anatomic(anaal stenosis,imperforatecanus,anteriorly displaced anus.intestinal stricture) Abnormal musculature(prune-belly syndrome,Gastroschisis,Down syndrome Intestinal nerve or muscle abnormalities(Hirschprung diease) Spinal cord defects(spinal cord trauma or spina bifida) Drugs(Anticholinergics or narcotics
Slide 12-

Metabolic disorders(Hypokalemia,hypercalcemia,hypotghyroidism,D.M) Intestinal disorders:(celiac disease,cow milk protein intolerance,meconium ileus,inflammatory bowel disease,tumour) Connective tissue disordersSLE,sclerderma) Psychiatric diagnosis(Anorexia nervosa)
Slide 13-

2. Organic Causes Hirschsprung’s disease *Clinical clues Delayed muconium passage > 48h or early onset of constipation Empty rectum on examination Normal anal tone Absence of ganglia in rectal sub mucosal biopsy Barium enema  transition zone Manometery --- absence of internal sphincter relaxation
Slide 14-

Conflict in training Stool retention  Pain in defecation  withholding the stools   distention of the rectum   Rectal sensation  necessitating a greater fecal mass to initiate the urge to defecate
Slide 15-

Complication of stool retention Impaction Abdominal pain Overflow diarrhea  leakage around the fecal mass Anal fissure Rectal bleeding Urinary tract infection
Slide 16-

Management: History and clinical examination should reduce the number of investigation e.g. anal fissure History of change in environment or diet Presence of hard impacted stools Barium study:?XRAY .large rectum or recto -segmoid .impaction of stool
Slide 17-

B. Elder Children He might present with recurrent abdominal pain He might develop soiling The elder child will eventually reach the stage where he is very quiet, withdrawn and isolated from his classmates Parents and child should participate in a group discussion and plan the management to help the child *If with soiling advise of Psychiatrist
Slide 18-

Medical Hypertonic phosphate enemas daily or every other day for 1 week. Mineral oil 30-60 mls twice daily between meals to minimize its effect in impairing the absorption of fat soluble vitamins --  with the response to stop within the period of about 6 months. Ensure that the child has sufficient fluid and fiber in the diet Bulk type of softness (Metamucil) maybe administered as the dose of mineral oil is tapered. Lactulose, senna, may have to be prescribed to break the vicious cycle of fecal retention and pain
Slide 19-

Dietary Measures Intake of fluid High residual diet, bran – whole wheat Fruit and vegetable Prune Juice Anal Dilatation Old method – local anesthesia Well lubricated little finger inserted into the anus and kept for 1 minute
Slide 20-

INFANTS *Treat the cause Simple constipation … correct diet … add fiber… treat anal fissure .. Softening the stool to break the cycle Daily stitz bath Application of Vaseline ointment after the bath Anesthetic ointment.
Slide 21-

Managements: Hx Onset Associated findings FTT  organic Ex Abdominal Rectal Signs of Hypothyroidism Explanation Common problem Will get better Physiology of defecation Long term managements up to 1 year
Slide 22-

Goals: Empty Rectum Clean out retained stool Enema Suppositories Senakot Bowel cleaning
Slide 23-

2. Bulky stool High fiber diet (bran)
Slide 24-

3. Improve habits Regular time of toilet after feed Stars chart Position- squatting De emotionalize home environment
Slide 25-

Functional Constipation: WHY MAY THE TREATMENT FAIL ?! Inadequate clean out  suppositories Inadequate dosage of medication On and off approach: Intermittent use of medication
Slide 26-

ppt slide no 26 content not found
Slide 27-

Malabsorption Objectives: Digestion Definition Identify major causes of malabsorption Know to work up for malabsorption
Slide 28-

Malabsorption Digestion Stomach ------- breakdown ingested food by rhythmic contraction gastric acids. Small bowel---- Intestinal secretion  digestion. *Brush Border
Slide 29-

Small bowel 2 halves Jejunum CHO maltose Fat F.A. mono glycerides Protien..di ,tri, tetra peptides + a.a. Minerals Vitamins Water Ileum Water B12 Bile salts
Slide 30-

Malabsorption Syndromes Malabsorptive disorders They are conditions that cause insufficient assimilation of ingested nutrients either as a result of mal digestion, or malabsorption. General presentation: Abdominal distention Pallor Foul smelling stools Bulky stools.. Normal… greasy…steatorrhea muscle wasting Poor weight gain … weight loss Growth retardation Clues: Acute diarrhea --- infection chronic diarrhea > 3 weeks ? Malabsorption Blood,FTT Overall appearance of the child
Slide 31-

I. Malabsorption according to age of presentation 1. From birth up to two years of age: Post infectious Protein intolerance Congenital microvillus inclusion disease. Glucose – galactose transport defects. Congenital chloride diarrhea Familial chronic villous atrophy Immune deficiency disease Cholestatic liver disease Gluten sensitive enteropathy Anatomical cause (short bowel syndrome) 2. Older children: Cystic fibrosis Crohn’s disease Gluten sensitive enteropathy Acquired lactose deficiency
Slide 32-

II. Malabsorption according to substances: Fat Celiac disease Cystic fibrosis OTHERS: Giardiasis Congenital intestinal malformation Crohn’s disease Biliary atrasia Liver cirrhosis
Slide 33-

2.Carbohydrate Glucose -galactose transport defect Genetic Lactose (Primary lactase deficiency) Sucrose (Congenital sucrase – isomaltase deficiency) Secondary celiac disease any chronic diarrhea
Slide 34-

3. Protein Follow any chronic diarrhea Enzyme deficiency (trypsinogen) Allergy… Cow’s milk protein 4. Vitamins Fat soluble Vit. Secondary to steatorhea B12 … Crohn’s
Slide 35-

III. Malabsorption according to site of defects. Mucosal Small intestinal injuries resulting in secondary deficiencies. - Celiac disease - Bacterial over growth - Cow’s milk enteropathy - Giardiasis - Rota virus infection - Chronic protracted diarrhea - Protein energy malnutrition - Crohn’s disease of small intestine - Short bowel syndrome - Drugs …neomycin … colchicines - Radiation enteritis
Slide 36-

2. None mucosal Pancreatic disease ------ cystic fibrosis Bile losses ---- bacterial overgrowth  deconjugation of bile acids  Cholestasis Lymphatic obstruction------ lymphagiactasia A Beta–lipo proteinemia
Slide 37-

How to approach: History: Is he/she thriving Weight/height Appetite Other symptoms --- edema Repetition of symptoms with reintroduction of certain foods e.g. Gluten Lactose Cow’s milk Stool Greasy Oil slik in the toilet Frothy – sugar intolerance Smell --- Rancid, CF -----foul, celiac
Slide 38-

Examination Growth chart Pallor --- Iron, folate Clubbing CF, IBD, CD Chest problem CF Distended abdomen CD Muscle hypotonia + wasting Nappy rash Rectal examination (prolapsed)
Slide 39-

Laboratory investigations: Stool 1.microscopic examination Fat droplet (stool + water + Sudan red stain) 72 hours stool collection Stool Giardia Cyst ELISA for Giardia antibodies. 2. Stool PH  5.6 (CHO) 3. Spot  antitrypsin level ( 2 days stool)
Slide 40-

4. Stool reducing substance Chromatography Clintest tab 10 drops water + 5 drops stool+tab (-ve -- 4+) Color coding 2 + or  suggest CHO malabsorption Sucrose is not reducing substance Should be hydrolyzed by HCl before analysis
Slide 41-

5. Stool osmolarity (stool electrolyte content) 290 - 2(Na + K ) meq/L  100 mosm/L  secretary as in cong chloride diarrhea  100 mosm/L  Osmotic diarrhea  CHO intolerance
Slide 42-

2. Blood CBC— blood film------- A canthocyte hypochromic, microcytic anemia macrocytosis Serum albumin Serum immunoglobulins Trypsinogen (screening) Nutrients in blood Iron .. Transferrin concentration folic acid –---- RBCs concentration , not serum Ca, Mg, Vit D., Vit A B12 -- bile salt Vit E + Serum lipids Vit K ( PT , PTT)
Slide 43-

3. Others Sweat chloride test Hydrogen breath test D-xylose test Schilling test (Vit B12)
Slide 44-

4. Diagnostic Procedure: Small bowel biopsy: 1. Duodenal mucosa Giardia trophozoite Colony count of bacteria Culture of proximal juice 2. For HIV parasitic bacteria or virus viral opportunistic entral pathogen 3. Gluten sensitive enteropathy Challenge test 4. Congenital microvillous inclusion disease 5. Eosinophillic gastroenteritis 6. Infectious disorders
Slide 45-

2. Imaging procedure X-ray – site of colon - e.g. intestinal mal rotation Ultra sound (biliary tree.. Pancreas) Barium contrast meal and follow through Barium enema
Slide 46-

Review of some disorders I. Disorders of CHO intolerance Symptoms Flatulence, Diarrhea, bloating, vomiting, abdominal cramping, barborygmi A. Congenital Disorders Lactose deficiency cong (rare) Acquired TX Lactose hydrolyzed milk. Lactid tab Sucrase deficiency: Recurrent watery diarrhea, stool PH below 6 Glucose – Galactose malabsorption. Very rare neonates severe hypoglycemia – acidosis TX fructose formula
Slide 47-

B. Acquired disorders: Secondary to acute viral OR bacterial gastro enteritis…. lactase def > sucrase Generally children tolerate lactose withen (3w-3m) Stool PH 6 +ve clinitest tab Secondary to celiac disease, Crohn’s disease, ulcerative colitis TX – lactose free diet
Slide 48-

II. Disorders of Proteins Cow’s milk protein sensitivity A topic individuals Jejunal atrophy Colonic bleeding Iron deficiency anemia unresponsive to treatment with oral iron. TX D/C milk Repeat challenge with carefully increasing dose majority will tolerate milk by two years. 40% intolerant to Soya protein.
Slide 49-

Celiac disease Allergy to Gliaden portion of gluten (wheat, Rye, Oats or barley) Screening antibodies Antigliadin IgA, Anti reticulin, Anti endomyseal EMA
Slide 50-

Celiac Sprue: Gluten sensitive enteropathy C/P Abdominal distention Weight loss –FTT irritability Vomiting Steotorrhea mild cases, IDA,,, short stature ,,,delayed puberty Investigation:  Serum Iron  folic acid  albumin Flat Glucose tolerance test EMA +ve,, ,+ve Antigliadin Small bowel biopsy 100% diagnostic - villous atrophy on a gluten free diet - Recurrence after a gluten challenge Treatment: Gluten free diet for life Prognosis: Strict diet - Normal growth – health - 1% lymphoma
Slide 51-

Causes of flat small intestinal mucosa:
Slide 52-

Mucoviscidosis Cystic fibrosis AR Defect: Mucus secreted by exocrine glands is abnormally thick and sticky due to defect in chloride permeability which lead to failure in maintaining the luminal hydration. It is an obstructive lesion in which a duct or airway passage is blocked by intra luminal mucous and other protein. 60% presents before 1 year. 85% before 5 years
Slide 53-

C.P. Most presented with failure to thrive frequent foul smelling stocl Rectal prolapse 18.5% by 1-2 Yr. 10% muconium illeus - a plug of muconium in the terminal ileum which lead to ischemic ulceration and peritonitis - delayed passage of muconium in neonate 10% Pancreatic fibrosis Exocrine insufficiency  malabsorption
Slide 54-

80% Recurrent chest infection Atelactasis  Bronchiactasis  Emphysema  Corpulmonal  death Rare Boys Azospermia  infertility Liver  obstructive jaundice biliary cirrhosis Gallbladder  Gall stones
Slide 55-

Investigation: 24 hour stool chymotripsin True test for pancreatic function : by low enzyme output from Pancreas, follow stimulation by secretin and cholecytokinin Sweat test. (Sweat chloride measurement)  60 meq/L -------- diagnostic If doubtful as is cases of edema , sweat test should be repeated once edema subside Treatment: Enteric coated – acid resistant oral pancreatic enzyme supplements Diet high in protein, low fat or MCT diet
Slide 56-

CYSTIC FIBROSIS A.R. Exocrine gland abnormalities  Electrolyte transport defect + inspissated mucous Sweat Salivary Pancreatic Pancreas Lung Liver vas Glands gland duct deference Bronchial Obstruction Obstruction and infection Defective Na + cl Defective HCO3 Pancreatic fibrosis Biliary duct male Absorption Secretion Obstruction infertility By gland Chronic Obstructive lung disease Pancreatic Biliary cirrhosis insufficiency Cor pulmonale mal absorption muconium ilieus
Slide 57-

Inflammatory bowel disease A. Croh’s disease: Regional enteritis Transmural inflammation with skip areas Genetic predisposition C/P Post prandial abdominal pain . ± diarrhea or constipation weight loss fever arthralgia /arthritis 2% Erythema nodosum Investigations:  ESR Anemia  albumin  iron : Proctoscopy Double contrast colon X-ray Rectal biopsy Treatment: Enteral or parentral nutrition Medicine - Prednisone - Sulfasalazine (if colonic involvement) - Azathoprine - Cyclophosphamide -70% surgical treatment
Slide 58-

B. Ulcerative colitis Mucosal inflammation ---rarely involve muscularis layer Toxic mega colon C/P bloody diarrhea + tenesmus Complication Hge Mega colon intractable symptoms Arthalgia / arthritis high risk of colonic cancer Treatment: Enteral and parentral nutrition medical: - Sulfasalazine oral - hydro cortison enema - systemic predisone - Cyclo sporins 25% surgical treatment colectomy if mega colon
Slide 59-

Thank You