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Biobran in Covid-19 Patient PowerPoint Presentation

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Description : Biobran is an Immune system booster and can be used in Covid-19 patient in early phase for recovery.

Tags : Biobran,Covid-19,Corona virus,flu,virus,covid 19,covid,corona,Immune system booster

Published on : Nov 17, 2021 | Views : 1958 | Downloads : 1

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Slide 1-

Role of Biobran in Covid-19 Patients
Slide 2-

Covid-19 COVID-19 is an infectious disease caused by the recently found virus known as SARS-CoV-2 (Severe Acute Respiratory Syndrome-Corona Virus-2)
Slide 3-

SYMPTOMS HIGH FEVER The body temperature can exceed 98.6 ºF HEADACHE The patient can suffer from headaches DRY COUGH Constant coughing with/without expelling mucus DYSPNOEA Breathing actually feels more difficult
Slide 4-

LOSS OF SMELL & TASTE FATIGUE DIARRHEA SYMPTOMS Recently there is repot of loss of Smell & Taste as early symptoms Patients feel fatigue during & in post Covid situation Some gets diarrhea as symptom of Covid-19
Slide 5-

Spread This virus is mainly spread by Respiratory Droplets. CONTACT COUGH SNEEZE
Slide 6-

Cell Enter & Replication
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Inflammation of both lungs PNEUMONIA SEVERE CONDITION But Covid-19 Virus pass the Mucus & Cilia defense and enter the Alveoli. Generally, Mucus & Cilia lining the tubes of Trachea, Bronchi and Bronchioles push out the germs and pathogen out of the airways through coughing. As this virus also weakens our immune system, it overwhelms our immune cells and cause cytokine storm. As a result, Alveoli gets inflamed and fills with fluid making it difficult for O2 and CO2 exchange. Develops Pneumonia. With Comorbidities, eventually leads to Death.
Slide 8-

How do we Defend/Cure this Virus ?
Slide 9-

THE IMMUNE SYSTEM Answer: Our own Defense Or Immune System
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Although the Covid-19 virus affects the immune system and downregulates them, Lymphocytes including NK cells continues to fight the Virus as they are greater in number compared to in Adults. STUDY OBSERVATIONS 1. NK Cells ACE2 receptors are upregulated in children and they work better because of less number of virus due to NK Cells. ACE2 receptors also have anti-inflammatory function. Because of that mild symptoms appears in children. 2. ACE2 Receptors As children are more prone to lung infection, their immune cells in lung are more active in exposure to any virus in lung. 3. Lung Immunity
Slide 12-

NK Cell Important part of Innate Immunity. First line of Immune Defense. Secret Perforin & Granzymes to kill viral infected cells. Compose 10%-15% of peripheral Lymphocytes. Early producers of IFN-ɣ Do not need prior exposure for their activity. Enhance target cell activity. Facilitates Adaptive Immunity.
Slide 13-

NK Cell Functions In Healthy Cells In Viral Infected and Cancer Cell
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Continued… IFN-ɣ CD107a IL-2 Dendritic Cells Adaptive Immunity Granzymes Perforin Apoptosis of infected cell Virus Infected Cell Bind
Slide 15-

Covid-19 in Adults
Slide 16-

NK Cell Exhaustion Regulatory T Cell NK Cell NKG2A 2. Suppressing Effect by Regulatory T Cell 1. Dysregulated Cell Receptor Signaling Results in- 1. Cytolytic activity 2. IFN-ɣ production 3. CD107a expression 4. IL-2 secretion
Slide 17-

SARS-CoV Study
Slide 18-

SARS-CoV & SARS-CoV-2 SARS-CoV-2 shares almost 80% Genome Sequence Similarity with SARS-CoV.
Slide 19-

Genome Sequence Similarity
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AT THE END As SARS-CoV-2 shares almost 80% Genomic Similarity of the SARS-CoV Virus and they behave almost in a same way, early management of the SARS-CoV-2 virus by Boosting Our Innate Immunity can save us from this dreadful pandemic disease.
Slide 21-

Considering this Pandemic Situation & Welfare of the Corona Patients Beacon Pharmaceuticals Ltd. Offers Trusted & Proven Immunomodulator
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Trusted & Proven Immunomodulator Biobran is Clinically Proven to Boost Our Immune System in Fighting Against Viruses and Diseases by Enhancing Activity of NK cell, T-cell & B-cell A Warrior in the Microworld
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A 3-month study with HCV patients
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A 3-month study with HCV patients n= 37 Biobran Group = 16 Control (PEG IFN + Ribavirin)= 21 Dose= 1gm/day Duration= 3 month p= 0.023 p<0.001
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NK Immunorestoration of Cancer Patients
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NK Immunorestoration of Cancer Patients n= 32 Prostate= 10 Breast= 12 Multiple Myeloma= 5 Leukemia= 5 Dose= 3g/day Duration= 1 to 2 weeks
Slide 27-

Increased CD107a Expression in Geriatric People
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Increased CD107a Expression in Geriatric People Dose= 500 mg/day Duration= 1 month n= 12 Biobran= 6 Placebo= 6
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Covid-19 Case Study
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THANK YOU