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AVIAN INFLUENZA PowerPoint Presentation

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Description : Check out this medical presentation on Influenza (Flu), which is titled "AVIAN INFLUENZA", to know about avian influenza.

Tags : Influenza, Flu, avian influenza

Published on : Aug 29, 2021 | Views : 314 | Downloads : 0

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AVIAN INFLUENZA
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AVIAN INFLUENZA What is it? How does it affect birds? How does it affect me?
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What is AI Virus
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What is AI Linda Stannard RNA Neuraminidase (9) Haemaglutinin (16)
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What is AI H-Highly P-Pathogenic A-Avian I-Influenza HPAI-H5N1
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Waterbirds (ducks, gulls and shorebirds) are the natural reservoir Role of wild birds Type A - wild and domestic birds, humans, pigs, horses and marine mammals. Types B & C - humans, less severe disease
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Subclinical/mild disease of the respiratory/GI tract Fecal-oral transmission route All AI endemic to waterfowl is low path AIV is in evolutionary “stasis” in waterfowl (H6 viruses isolated 81 years apart were 95.3% identical) Avian Influenza in Waterfowl Takashi Koike
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Season Spring Summer Fall Winter H3, H4, H6 most common ~10% ~60%
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Prevalence of H5N1 in wild birds-2006 Africa. 0/3500 samples from Chad, Mali, Ethiopia and Morocco (Vincent Martin, Nairobi meeting April 2006). Czech Republic 12/2038 (0.53%) dead wild birds positive (OIE Dis Info v19 #17). France 66/14,000 (0.47%) wild birds positive (NDTV, 4/22/06). UK 1/891 (0.11%) dead swans H5N1 positive (0.11%) (DEFRA, 4/21/06).
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Human disease that spreads beyond large regions (e.g. between continents) PANDEMIC 1) Subtype 2) Illness 3) Transmissible
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1997 2003
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First H5N1 Detection Wild bird detections
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Qinghai Outbreak - May 2005 Wild birds affected at Qinghai Nature Reserve Mainly bar-headed geese (Anser indicus) Gulls (2 species) Liu et al, 2005. Science Source: Liu et al., 2005. Science.
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Poultry? Wild birds? H5N1-Who’s spreading it?
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1997 2003
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Distribution of AI receptor in humans vs birds
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CLINICAL SIGNS OF H5N1 IN HUMANS Fever Headache Muscle pain Diarrhea 3-4 days illness onset 12-29 days death
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CASE FATALITY RATE (Probability of dying if you get it) Probability BOTTOM LINE: 1) H5N1 is hard to get. 2) If you get it, odds of dying are 50:50.
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What is the risk of my getting H5N1? It’s all relative Handling live sick birds with known H5N1 Handling live sick birds Necropsying dead bird Swabbing live bird w. gloves Picking up dead bird w. gloves Sitting in this workshop H5N1 has not been found in North or South America
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Questions?