Download Free Medical Adenoid Cystic Carcinoma AdCC - Cylindroma PowerPoint Presentation

Adenoid Cystic Carcinoma AdCC - Cylindroma PowerPoint Presentation

DOWNLOAD MEDICAL POWERPOINT PRESENTATION

About This Presentation

Description : Check out this medical presentation on cancer titled "Adenoid Cystic Carcinoma(AdCC) - Cylindroma" to know about one of the more common salivary gland malignancies (MEC / PLGA / AdCC), originally called a cylindroma.

Tags : Cancer, Adenoid Cystic Carcinoma, AdCC, Cylindroma, salivary gland, malignancies, MEC, PLGA, histopathologic features, myoepithelial cells, ductal cells, maxillary sinus, submandibular gland

Published on : May 05, 2021 | Views : 1867 | Downloads : 3

Shareable Url :

Embed Code :

Comment

Transcript

Slide 1-

Adenoid Cystic Carcinoma(AdCC) cylindroma
Slide 2-

one of the more common salivary gland malignancies (MEC / PLGA / AdCC) Because of its distinctive histopathologic features, it was originally called a cylindroma A high grade malignancy
Slide 3-

ppt slide no 3 content not found
Slide 4-

Histopathologic Features composed of a mixture of myoepithelial cells and ductal cells that can have a varied arrangement Three major patterns: Cribriform Tubular solid Usually a combination of these is seen
Slide 5-

The cribriform pattern is the most classice characterized by islands of basaloid epithelial cells that contain multiple cylindric, cystlike spaces resembling Swiss cheese cystlike spaces often contain a mildly basophilic mucoid material, a hyalinized eosinophilic product, or a combined mucoid hyalinized appearance. homogeneous acidophilic material
Slide 6-

small and cuboidal, cells deeply basophilic nuclei little cytoplasm fairly uniform Rare mitotic activity Cribriform (Swiss cheese)
Slide 7-

Normal salivary glands Adjacent with tumor
Slide 8-

Cribriform pattern
Slide 9-

The tubular lumina can be lined by one to several layers of cells (ductal cells and myoepithelial cells) tubular pattern occur as multiple small ducts or tubules within a hyalinized stroma
Slide 10-

tubular pattern
Slide 11-

hyalinized "stroma
Slide 12-

solid variant consists of larger islands or sheets of tumor cells little tendency toward duct or cyst formation
Slide 13-

cellular pleomorphism and mitotic activity small and cuboidal, cells deeply basophilic nuclei little cytoplasm fairly uniform Solid Cribriform
Slide 14-

as well as focal necrosis in the center of the tumor islands, may be observed
Slide 15-

A highly characteristic but no pathognomonic perineural invasion which probably corresponds to the common clinical finding of pain in these patients a swirling arrangement around nerve bundles This marked tendency to proliferate around and along nerves for great distances accounts for the tumor's marked tendency to recur.
Slide 16-

Tumors with a solid histopathologic pattern are associated with a worse outlook the prognosis is poorest for tumors arising in the maxillary sinus and submandibular gland. The end