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Red Blood Cell Physiology PowerPoint Presentation

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Description : Check out this medical PowerPoint presentation titled "Red Blood Cell Physiology” by Dr Sunita Mittal.

This medical PowerPoint presentation is about red blood cells (RBCs) are also known as erythrocytes. Red blood cells play a vital role in the transport of oxygen from the lungs to the body tissues and the removal of carbon dioxide from the tissues back to the lungs. RBCs are biconcave in shape, disc-shaped cells that are about 7.5 micrometers in diameter and 2.5 micrometers thick at their thinnest point. The shape of RBCs provides them with a large surface area to volume ratio, which allows for efficient gas exchange.

The primary function of RBCs is to carry oxygen from the lungs to the tissues and carbon dioxide from the tissues to the lungs. RBCs contain hemoglobin, a protein that binds to oxygen and carbon dioxide. Hemoglobin is made up of four protein chains, each of which contains a heme group. The heme group contains iron, which binds to oxygen and carbon dioxide. Each RBC contains about 270 million hemoglobin molecules.

RBCs are produced in the bone marrow through a process called erythropoiesis. The production of RBCs is regulated by a hormone called erythropoietin, which is produced by the kidneys. When the oxygen-carrying capacity of the blood is reduced, the kidneys produce more erythropoietin, which stimulates the bone marrow to produce more RBCs.

The lifespan of RBCs is about 120 days. As they age, they become less flexible and more fragile, and they are eventually removed from circulation by the spleen and liver. The breakdown of RBCs produces bilirubin, a yellow pigment that is excreted in the bile and gives feces their characteristic color.

In summary, RBCs are crucial in the transport of oxygen and carbon dioxide in the body. Their shape, size, and content of hemoglobin make them ideal for this function. The production of RBCs is regulated by erythropoietin, and their lifespan is about 120 days. The breakdown of RBCs produces bilirubin, which is excreted in the bile and gives feces their characteristic color.

Tags : Red Blood Cell Physiology, red blood cells, RBCs, erythrocytes, Hematology, Hematology PowerPoint presentation

Published on : May 29, 2023 | Views : 2213 | Downloads : 0

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Slide 1-

Red Blood Cell Physiology Dr Sunita Mittal
Slide 2-

Morphological Features of RBCs Functions of the RBCs Hematological Indices Learning Objectives
Slide 3-

RBC are also known as erythrocytes or red blood corpuscles as it contains haemoglobin which turns red on binding with oxygen. It also carries carbon dioxide away from tissues to lungs. It contains certain antigens on its surface membrane that determine blood groups and makes basis of whole blood transfusion physiology. Red Blood Cells
Slide 4-

Clinical Application : Since RBC uses glucose constantly from plasma, whenever blood glucose level is to be tested, the sample is taken in the fluoride vial Red Blood Cells
Slide 5-

Red Blood Cells- Morphology-Size RBCs are anucleated discs RBC count : 4-6 million/mm3, Life span - 120 days. Central pallor is seen due to presence of less haemoglobin molecule in the centre. Size – Diameter: 7-7.8 µm, Thickness at the periphery-2.2 µm and Centre - 1 µm
Slide 6-

Shape - Normal biconcave disc Biconcave shape has many advantages: 1. Flexibility RBCs 2. Greater surface area/volume ratio Red Blood Cells- Shape
Slide 7-

RBCs Count-4-6 million/mm 3 Hb content-14-16 gm/dl O2 carrying Capacity of blood-1 gm Hb binds to 1.34 ml of O2 PCV=45±2 ml/100 ml of blood Red Blood Cells- Normal values
Slide 8-

Hematological Indices Red blood cell indices are blood tests that provide information about the average volume or size (MCV) and hemoglobin content (MCH, MCHC) of red blood cell.
Slide 9-

Mean corpuscular volume (MCV) is the average volume of a single rbc. We need values of: ▪ RBC count ▪ PCV = PCV X 10 µ³ RBCs = 80-100 µ³ Mean Corpuscular Volume (MCV)
Slide 10-

Mean Corpuscular Hemoglobin (MCH) Mean corpuscular hemoglobin (MCH) is the average amount of hemoglobin of a single rbc. We need values of: ▪ RBC count ▪ Hb = Hb X 10 pg RBCs = 27-32 pg
Slide 11-

Mean Corpuscular Hemoglobin Conc. (MCHC) Mean corpuscular hemoglobin Concentration (MCHC) is the average concentration of hemoglobin per unit volume of red blood cells. We need values of: ▪ PCV ▪ Hb = Hb X 100 g PCV 32-36 %
Slide 12-

What is normal RBC Count- a. 4000-6000/mm3 b. 4lac-6 lac/mm3 c. 4 million to 6 million/mm3 d. 4 billion to 6 billion/mm3 What is the life span of RBCs- a. 1 month b. 2 months c. 3 months d. 4 months What is the term used to describe a cell of normal color? A.-Normochromic B. Hypochromic C. Polychromic D Euchromic Self Asessment
Slide 13-

What are the formula and normal value of MCV------------------------------- What are the formula and normal value of MCH------------------------------- What are the formula and normal value of MCHC----------------------------- What are the causes of Normocytic normochromic anemia----------------- What are the causes of Microcytic hypochromic anemia--------------------- What are the causes of Macrocytic anemia---------------------------------- Self Asessment
Slide 14-

Thank you