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Description : Check out this medical presentation on Genetics, which is titled "Human Inheritance", to learn about Human Inheritance, human traits controlled by gene.

Tags : Genetics, Human Inheritance, human traits, gene

Published on : Aug 29, 2021 | Views : 1994 | Downloads : 8

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Slide 1-

Human Inheritance Chapter 4 Section 1
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You Have Your Mother’s Eyes Have you ever heard someone say “He’s the spitting image of his dad” or “She has her mother’s eyes”? Children often resemble their parents. The reason for this is that alleles for eye color, hair color, and thousands of other traits are passed from parents to their children. People inherit some alleles from their mother and some from their father. This is why most people look a little like their mother and a little like their father.
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Traits Controlled By Single Genes Many human traits are also controlled a single gene with one dominant allele and one recessive allele. As with tall and short pea plants, these human traits have two distinctly different phenotypes, or physical appearances. For example, a widow’s peak is a hairline that comes to a point in the middle of the forehead. The allele for a widow’s peak is dominant over the allele for a straight hairline.
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Multiple Alleles Some human traits are controlled by a single gene that has more than two alleles. Such a gene is said to have multiple alleles – three or more forms of a gene that code for a single trait. You can think of multiple alleles as being like flavors of pudding. Pudding usually comes in more flavors than just chocolate and vanilla!
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Multiple Alleles cont. Even though a gene may have multiple alleles, a person can carry only two of those alleles. This is because chromosomes exist in pairs. One human trait that is controlled by a gene with multiple alleles is blood type.
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Blood Types There are four main blood types – A, B, AB, and O. Three alleles control the inheritance of blood types. The allele for blood type A and the allele for blood type B are codominant. The codominant alleles are written as capital letters with superscripts – IA for blood type A, and IB for blood type B. The allele for blood type O is recessive and written like i. A person who inherits an allele for both A blood type and B blood type are codominant. Neither allele is masked and results in blood type AB.
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Traits Controlled by Many Genes Some human traits show a large number of phenotypes because the traits are controlled by many genes. The genes act together as a group to produce a single trait. At least four genes control height in humans, so there are many possible combinations of genes and alleles.
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Skin Color Like height, skin color is determined by many genes. Human skin color ranges from almost white to nearly black, with many shades in between. Skin color is controlled by at least three genes. Each gene, in turn, has at least two possible alleles. Various combinations of alleles at each of the genes determine the amount of pigment that a person’s skin cells produce. Thus, a wide variety of skin color is possible
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The Effect of Environment The effects of genes are often altered by the environment – the organism’s surroundings. For example, people’s diets can affect their height. A diet lacking in protein, minerals, and vitamins can prevent a person from growing to his or her potential maximum height. Since the late 1800’s, the average height of adults in the United States has increased by almost 10 centimeters. During that time, American diets have become more healthful. Other factors, such as medical care and living conditions, have also improved since the 1800s.
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Male or Female Factors that determine whether a baby is a boy and a girl are determined by genes on chromosomes. Among the 23 pairs of chromosomes in each body cell is a single pair of chromosomes called sex chromosomes. The sex chromosomes determine whether the baby is a male or female.
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Sex Chromosomes The sex chromosomes are the only pair of chromosomes that do not always match. If you are a female, your two sex chromosomes match. The two chromosomes are called X chromosomes. If you are a male, your sex chromosomes do not match. One of your sex chromosomes is a Y chromosome. The Y chromosome is much smaller than the X chromosome.
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50 – 50 Chance Since both the female’s sex chromosomes are X chromosomes, all eggs carry one X chromsome. Males, however, have two different sex chromosomes. This means that half of a male’s sperm cells carry and X chromosome, while half carry a Y chromosome. When a sperm cell with an X chromosome fertilizes an egg, the egg will have two X chromosomes which will result in a girl. When a sperm cell with a Y chromosome fertilizes an egg, the egg will have one X chromosome and one Y chromosome resulting in a boy. *The sperm determines the sex of the child.
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Punnett Square Father XY X Y Mother XX X X
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Sex-Linked Genes Some human traits occur more often in one sex than the other. The genes for those traits are often carried on the sex chromosomes. Genes on the X and Y chromosomes are often called sex-linked genes because their alleles are passed from parent to child on a sex chromosome. Traits controlled by sex-linked genes are called sex-linked traits.
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Dominant and Recessive Alleles Sex-linked genes can have dominant and recessive alleles. Females have two X chromosomes, and males have one X and one Y chromosome. In females, a dominant allele on one X chromosome will mask the recessive allele on the other X chromosome. This is not the same for males. In males, there is not matching alleles on the Y chromosome to mask the allele on the X chromosome. As a result, any allele on the X chromosome, even a recessive allele, will produce the trait in a male who inherits it. Because males only have one X chromosome, they are more likely than females to have a sex-linked trait that is controlled by a recessive allele.
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Examples An example of a sex-linked trait that is controlled by a recessive allele is red-green colorblindness. A person with red-green colorblindness can not distinguish between red and green. Many more males than females have red-green colorblindness. If you look at page 117, you can see a Punnett square for this trait. Notice that the mother is a carrier. A carrier is a person who has one recessive allele for a trait and dominant allele. The carrier does not have the trait, but can pass the recessive allele on to his or her offspring. In the case of sex-linked traits, females can only be carriers.
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Pedigree One important tool that geneticists use to trace the inheritance of traits in humans is a pedigree tree. A pedigree is a chart or “family tree” that tracks which members of a family have a particular trait. The trait recorded in a pedigree can be an ordinary trait such as widow’s peak, or it can be a sex-linked trait such as colorblindness. Look on page 118, to see how colorblindness is traced through a family